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46

RESULTS

Median (5 and 95 percentile) blood lead concentration in

the participants was 16.6 µg/l (7.5 and 39 µg/l). An optimal

multivariate linear regression model for log-transformed

blood lead indicated that cervid game meat consumption

once a month or more was associated with approximately 31%

increase in blood lead concentrations. The increase seemed

to be mostly associated with consumption of minced cervid

meat, particularly purchased minced meat (Figure 1). However,

many participants with high game meat intake over a long

period of time had low blood lead concentrations. Cervid meat

together with the number of bullets shot per year, years of

(A)

Age-adjusted blood lead by frequency of game consumption.

(B)

Age-adjusted blood lead by tertiles of intake of mincedmeat

frommoose or deer, separately for men and women. Blood lead

means in the three men tertiles were 15.5, 23.0 and 26.7 μg/l, while

the correspondingmeans for women were 13.7, 15.7 and 18.4 μg/l,

respectively. Minced cervidmeat intake was associated with total

game intake at low andmoderate game intakes, but not at the

highest intakes.

(C)

Age - adjusted blood lead by tertiles of intake of meat fromgame,

except for mincedmeat frommoose or deer, for men andwomen. No

corrections have beenmade for intake of mincedmeat. Men in the

highest tertile had slightly lower blood lead levels than those in the

middle tertile, 26.7 vs.24.7 μg/l, but the differencewas not significant

(0.1<P<0.2). FromMeltzer et al. (2013).

game consumption, self-assembly of bullets, wine consumption

and smoking jointly accounted for approximately 25% of the

variation in blood lead concentrations, while age and sex

accounted for 27% of the variance. Blood lead concentrations

increased approximately 18% per decade of age, and men

had on average 30% higher blood lead concentrations than

women. Hunters who assembled their own ammunition had

52% higher blood lead concentrations than persons not making

ammunition. In conjunction with minced cervid meat, wine

intake was significantly associated with increased blood lead.

The proportion of participants with blood lead levels exceeding

the EFSA BMDLs (Table 1) is illustrated in Figure 2.

Figure 1:

Age-adjusted blood lead by frequency of consumption

Helle K. Knutsen, Anne-Lise Brantsæter, Jan Alexander & Helle M. Meltzer